We have two research projects available to Bearded Collies. One is on DNA markers of Addison's disease and the other is on juvenile cataracts. Both studies are under the auspices of the AKC Canine Health Foundation. Please consider participating if your dog is eligible. Researchers in both studies will maintain confidentiality of participants. Be aware that it is impossible to predict when the projects will be completed and there will be answers.
Addison's Disease. The project goals are to identify and and determine inheritance mode of DNA markers for Addison's disease in Bearded Collies.
Those affected with Addison's disease, their healthy littermates, parents, and grandparents; possibly offspring by other matings of the parents (ask the researcher)
Normal dogs with no known history of Addison's disease in the family.
New Investigator. Beginning March 1, 2000, the project is transferred to Dr. Anita Oberbauer at the University of California, Davis. With this change, it will involve submitting a pedigree and obtaining cheek swabs for DNA. This methodology for DNA collection is simpler for both the dog and owner as it does not require a visit to the veterinarian. The quality of DNA is comparable to that obtained from blood specimens.
Previous Investigator. Dr. Ry Wagner, University of Oregon from the fall of 1998 through 1999. In that phase, blood specimens for DNA and pedigrees were collected. All material from Dr. Wagner's laboratory will be transferred to Dr. Oberbauer's laboratory in March or April. Click here to read Dr. Wagner's first six month progress report from spring 1999 and a glossary of genetic research terms.
Dog families of Standard Poodles and Leonbergers will be eligible for the project starting the spring of 2000. Please contact your breed health representative initially. Each will be able to guide you in the process.
Juvenile Cataracts. The project goals are to identify genetic markers and to determine the mode of inheritance of juvenile cataracts in multiple breeds.
Families with a cataract affected dog - littermates, parents, grandparents, and offspring of affected dogs, preferably with recent veterinary ophthalmologic exams.
It involves providing a blood specimen, pedigree, and copy of the ophthalmologic exam.